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Carboxylesterase 2 (CES2)
Carboxylesterase 2 (CES2)
CE-2; CES2A1; PCE-2; iCE; Intestine,Liver; Methylumbelliferyl-acetate deacetylase 2; Cocaine esterase
Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters.
The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
KER515Hu
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Carboxylesterase 2 (CES2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Carboxylesterase 2 (CES2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Carboxylesterase 2 (CES2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Carboxylesterase 2 (CES2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Carboxylesterase 2 (CES2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Carboxylesterase 2 (CES2) CLIA assay for Antigen Detection
Reference
"Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver." Biochem. Biophys. Res. Commun. 233:117-120(1997) [PubMed ] [Europe PMC ] [Abstract ]
"Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin." J. Biol. Chem. 272:14769-14775(1997) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The full-ORF clone resource of the German cDNA consortium." BMC Genomics 8:399-399(2007) [PubMed ] [Europe PMC ] [Abstract ]
"The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." J. Proteome Res. 8:651-661(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
"Catalog of 680 variations among eight cytochrome p450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population." J. Hum. Genet. 48:249-270(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2)." Drug Metab. Pharmacokinet. 18:327-332(2003) [PubMed ] [Europe PMC ] [Abstract ]
