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Cysteine Rich Secretory Protein 3 (CRISP3)

CRS3; Aeg2; CRISP-3; SGP28; Specific granule protein of 28 kDa

Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma.Human cysteine-rich secretory protein 3 (CRISP-3; also known as SGP28) belongs to a family of closely related proteins found in mammals and reptiles. Some mammalian CRISPs are known to be involved in the process of reproduction, whereas some of the CRISPs from reptiles are neurotoxin-like substances found in lizard saliva or snake venom. Human CRISP-3 is present in exocrine secretions and in secretory granules of neutrophilic granulocytes and is believed to play a role in innate immunity.
Electronic profiling of publicly available expressed sequence tag databases identified a gene, cysteine-rich secretoryprotein-3 (CRISP-3), that is up-regulated in prostate cancer, and of which the expression is relatively prostate-specific.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Hu01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Hu01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Hu01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Hu01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Hu01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Mu01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Mu01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Mu01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Mu01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Mu01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Ra01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Ra01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Ra01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Ra01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Ra01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Ca01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Ca01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Ca01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Ca01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Ca01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Po01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Po01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Po01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Po01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Po01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Bo01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Bo01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Bo01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Bo01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Bo01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Rb01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Rb01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Rb01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Rb01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Rb01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR458Mo01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAR458Mo01 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
PAR458Mo01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IF.
Assay Kits CLR458Mo01 CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA assay for Antigen Detection
ELR458Mo01 ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein."
FEBS Lett. 380:246-250(1996) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3."
Eur. J. Biochem. 236:827-836(1996) [PubMed] [Europe PMC] [Abstract]

"Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma."
Biochemistry 43:12877-12886(2004) [PubMed] [Europe PMC] [Abstract]