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Crystallin Gamma S (CRYgS)

CRYG8

Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins.
CRYgS encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R445Mu01 Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
PR445Mu01 Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits KER445Mu ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Crystallin Gamma S (CRYgS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Crystallin Gamma S (CRYgS) Bioactivity
Antibodies NONE Monoclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Crystallin Gamma S (CRYgS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Crystallin Gamma S (CRYgS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Crystallin Gamma S (CRYgS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Crystallin Gamma S (CRYgS) CLIA assay for Antigen Detection

Reference

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Primary structure of beta s-crystallin from human lens."
Biochem. J. 287:375-381(1992) [PubMed] [Europe PMC] [Abstract]

"The human gene for gammaS-crystallin: alternative transcripts and expressed sequences from the first intron."
Mol. Vis. 6:79-84(2000) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The complete sequence of human lens gamma s-crystallin."
Biochem. J. 307:407-410(1995) [PubMed] [Europe PMC] [Abstract]

"Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens."
J. Biol. Chem. 272:2268-2275(1997) [PubMed] [Europe PMC] [Abstract]

"The X-ray crystal structure of human gamma S-crystallin C-terminal domain."
J. Biol. Chem. 277:4199-4205(2002) [PubMed] [Europe PMC] [Abstract]

"Gamma-S crystallin gene (CRYGS) mutation causes dominant progressive cortical cataract in humans."
J. Med. Genet. 42:706-710(2005) [PubMed] [Europe PMC] [Abstract]