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Cullin 9 (CUL9)
Cullin 9 (CUL9)
PARC; H7AP1; P53-Associated Parkin-Like Cytoplasmic Protein; UbcH7-associated protein 1
PARC directly interacted and formed an approximately 1-MD complex with p53 in the cytoplasm of unstressed cells. In the absence of stress, inactivation of PARC induced nuclear localization of endogenous p53 and activated p53-dependent apoptosis. Overexpression of PARC promoted cytoplasmic sequestration of ectopic p53.abnormal cytoplasmic localization of p53 was observed in a number of neuroblastoma cell lines; RNA interference-mediated reduction of endogenous PARC significantly sensitized these neuroblastoma cells in the DNA damage response. These results revealed that PARC is a critical regulator in controlling p53 subcellular localization and subsequent function.PARC also has a unique motif that is highly homologous to the C terminus of cullin proteins that the authors referred to as the C-terminal cullin homology domain.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
MR438Hu21
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
PR438Hu01
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cullin 9 (CUL9) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cullin 9 (CUL9) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cullin 9 (CUL9) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cullin 9 (CUL9) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cullin 9 (CUL9) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cullin 9 (CUL9) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cullin 9 (CUL9) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cullin 9 (CUL9) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cullin 9 (CUL9) CLIA assay for Antigen Detection
Reference
"Parc: a cytoplasmic anchor for p53." Cell 112:29-40(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The full-ORF clone resource of the German cDNA consortium." BMC Genomics 8:399-399(2007) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro." DNA Res. 5:169-176(1998) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1." J. Biol. Chem. 274:30963-30968(1999) [PubMed ] [Europe PMC ] [Abstract ]
"Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development." Mol. Cell. Biol. 25:5579-5589(2005) [PubMed ] [Europe PMC ] [Abstract ]
"PARC and CUL7 form atypical cullin RING ligase complexes." Cancer Res. 67:2006-2014(2007) [PubMed ] [Europe PMC ] [Abstract ]
"CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity." Mol. Cell 54:805-819(2014) [PubMed ] [Europe PMC ] [Abstract ]
