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Latrophilin 2 (LPHN2)
Latrophilin 2 (LPHN2)
CIRL2; CL2; LEC1; LPHH1; Latrophilin 1; Latrophilin homolog 1; Calcium-independent alpha-latrotoxin receptor 2
Latrophilin-2 is a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits being non-covalently bound at the cell membrane.The 4,209-bp open reading frame of the 7-kb LPHH1 transcript encoded a peptide that showed approximately 65% identity to rat latrophilin, a G-coupled, 7-span transmembrane protein that binds alpha-latrotoxin. Surprisingly, while expression of the rat gene was strictly restricted to neurologic and perhaps some endocrine cells, the human sequence appeared to be expressed very widely in all normal tissues tested.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
R401Ra01
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
PR401Ra01
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection
Reference
"Isolation and characterisation of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer." Oncogene 17:3513-3519(1998) [PubMed ] [Europe PMC ] [Abstract ]
"Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines." Biochim. Biophys. Acta 1491:75-92(2000) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." DNA Res. 5:277-286(1998) [PubMed ] [Europe PMC ] [Abstract ]
"Discovery of tissue-specific exons using comprehensive human exon microarrays." Genome Biol. 8:R64.1-R64.16(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." J. Proteome Res. 8:651-661(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Sci. Signal. 4:RS3-RS3(2011) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]