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Latrophilin 2 (LPHN2)

CIRL2; CL2; LEC1; LPHH1; Latrophilin 1; Latrophilin homolog 1; Calcium-independent alpha-latrotoxin receptor 2

Latrophilin-2 is a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits being non-covalently bound at the cell membrane.The 4,209-bp open reading frame of the 7-kb LPHH1 transcript encoded a peptide that showed approximately 65% identity to rat latrophilin, a G-coupled, 7-span transmembrane protein that binds alpha-latrotoxin. Surprisingly, while expression of the rat gene was strictly restricted to neurologic and perhaps some endocrine cells, the human sequence appeared to be expressed very widely in all normal tissues tested.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R401Ra01 Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
PR401Ra01 Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Latrophilin 2 (LPHN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Latrophilin 2 (LPHN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Latrophilin 2 (LPHN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Latrophilin 2 (LPHN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Latrophilin 2 (LPHN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Latrophilin 2 (LPHN2) CLIA assay for Antigen Detection

Reference

"Isolation and characterisation of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer."
Oncogene 17:3513-3519(1998) [PubMed] [Europe PMC] [Abstract]

"Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines."
Biochim. Biophys. Acta 1491:75-92(2000) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]

"Discovery of tissue-specific exons using comprehensive human exon microarrays."
Genome Biol. 8:R64.1-R64.16(2007) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]