Latrophilin 3 (LPHN3)

CIRL3; LEC3; Calcium-independent alpha-latrotoxin receptor 3; Lectomedin-3

SPN	R400
HGNC	20974
MGI	2441950
PubMed	20157310
RGD	620836
UniProt	Q9HAR2
Wiki	LPHN3

Latrophilin-3 is a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.

Latrophilin 3forms a heterodimer, consisting of a large extracellular region (p120) non-covalently linked to a seven-transmembrane moiety (p85)

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	R400Hu01	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	MR400Hu22	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	PR400Hu01	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	KER400Hu	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Latrophilin 3 (LPHN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Latrophilin 3 (LPHN3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Latrophilin 3 (LPHN3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Latrophilin 3 (LPHN3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Latrophilin 3 (LPHN3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Latrophilin 3 (LPHN3)	CLIA assay for Antigen Detection

Reference

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]

"Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility."
Am. J. Med. Genet. B Neuropsychiatr. Genet. 156:11-18(2011) [PubMed] [Europe PMC] [Abstract]