Fibulin 3 (FBLN3)
EFEMP1; DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; EGF-Containing Fibulin-Like Extracellular Matrix Protein 1; Fibrillin-Like; Extracellular protein S1-5
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Hu01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Hu01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Hu01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Hu01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Hu01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Mu01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Mu01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Mu01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Mu01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Mu01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Ra01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Ra01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Ra01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Ra01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Ra01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Ca01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Ca01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Ca01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Ca01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Ca01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Po01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Po01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Po01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Po01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Po01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Bo01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Bo01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Bo01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Bo01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Bo01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Rb01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Rb01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Rb01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Rb01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Rb01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR375Mo01 | Recombinant Fibulin 3 (FBLN3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR375Mo01 | Monoclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IP. |
| PAR375Mo01 | Polyclonal Antibody to Fibulin 3 (FBLN3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR375Mo01 | CLIA Kit for Fibulin 3 (FBLN3) | CLIA assay for Antigen Detection |
| ELR375Mo01 | ELISA Kit for Fibulin 3 (FBLN3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"An overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesis."
Mol. Cell. Biol. 15:120-128(1995) [PubMed] [Europe PMC] [Abstract]
"Structure and chromosomal assignment of the human S1-5 gene (FBNL) that is highly homologous to fibrillin."
Genomics 35:590-592(1996) [PubMed] [Europe PMC] [Abstract]
"Sequence, recombinant expression and tissue localization of two novel extracellular matrix proteins, fibulin-3 and fibulin-4."
Matrix Biol. 18:469-480(1999) [PubMed] [Europe PMC] [Abstract]
"EFEMP1 is not associated with sporadic early onset drusen."
Ophthalmic Genet. 22:27-34(2001) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration."
Proc. Natl. Acad. Sci. U.S.A. 99:13067-13072(2002) [PubMed] [Europe PMC] [Abstract]
"Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1). Implications for macular degenerations."
J. Biol. Chem. 279:30469-30473(2004) [PubMed] [Europe PMC] [Abstract]
"EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells."
Biol. Chem. 390:1293-1302(2009) [PubMed] [Europe PMC] [Abstract]
"ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain."
Matrix Biol. 28:160-169(2009) [PubMed] [Europe PMC] [Abstract]
"Fibulin-3 is uniquely upregulated in malignant gliomas and promotes tumor cell motility and invasion."
Mol. Cancer Res. 7:1756-1770(2009) [PubMed] [Europe PMC] [Abstract]
"Fibulin-3 negatively regulates chondrocyte differentiation."
Biochem. Biophys. Res. Commun. 391:1116-1121(2010) [PubMed] [Europe PMC] [Abstract]
"Resveratrol-induced changes of the human adipocyte secretion profile."
J. Proteome Res. 11:4733-4743(2012) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"A single EFEMP1 mutation associated with both malattia Leventinese and Doyne honeycomb retinal dystrophy."
Nat. Genet. 22:199-202(1999) [PubMed] [Europe PMC] [Abstract]
"Dominant radial drusen and Arg345Trp EFEMP1 mutation."
Am. J. Ophthalmol. 131:810-812(2001) [PubMed] [Europe PMC] [Abstract]
"The R345W mutation in EFEMP1 is pathogenic and causes AMD-like deposits in mice."
Hum. Mol. Genet. 16:2411-2422(2007) [PubMed] [Europe PMC] [Abstract]