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Kinesin Family, Member 1A (KIF1A)

ATSV; UNC104; C2orf20; Axonal Transport Of Synaptic Vesicles; Microtubule-based motor KIF1A; Unc-104- and KIF1A-related protein

KIF1A is a member of the kinesin family. This protein is highly similar to mouse heavy chain kinesin member 1A protein which is an anterograde motor protein that transports membranous organelles along axonal microtubules. It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport. There are multiple polyadenylation sites found in this gene.
This switch-like transition for movement could be shifted to lower PtdIns(4,5)P2 concentrations by the addition of cholesterol/sphingomyelin or GM1 ganglioside/cholera toxin, conditions that produced raft-like behavior of Unc104 bound to lipid bilayers. The authors concluded that clustering of Unc104 in PtdIns(4,5)P2-containing rafts provides a trigger for membrane transport.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R301Hu01 Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies MR301Hu21 Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
PR301Hu01 Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits KER301Hu ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Kinesin Family, Member 1A (KIF1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Kinesin Family, Member 1A (KIF1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Kinesin Family, Member 1A (KIF1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Kinesin Family, Member 1A (KIF1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Kinesin Family, Member 1A (KIF1A) CLIA assay for Antigen Detection

Reference

"Characterization of a kinesin-related gene ATSV, within the tuberous sclerosis locus (TSC1) candidate region on chromosome 9q34."
Genomics 33:421-429(1996) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"KIF1A, an axonal transporter of synaptic vesicles, is mutated in hereditary sensory and autonomic neuropathy type 2."
Am. J. Hum. Genet. 89:219-230(2011) [PubMed] [Europe PMC] [Abstract]

"Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability."
Am. J. Hum. Genet. 88:306-316(2011) [PubMed] [Europe PMC] [Abstract]

Erratum
Am. J. Hum. Genet. 88:516-516(2011)

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis."
Genome Res. 21:658-664(2011) [PubMed] [Europe PMC] [Abstract]