Kisspeptin Receptor (KISS1R)
AXOR12; GPR54; KiSS1-Derived Peptide Receptor; G Protein-Coupled Receptor 54; Hypogonadotropin-1; Kisspeptins receptor; Metastin receptor
Kisspeptin is encoded by the metastasis suppressor gene KISS1, which is expressed in a variety of endocrine and gonadal tissues. Activation of the kisspeptin receptor is linked to the phospholipase C and inositol trisphosphate second messenger cascades inside the cell.
Kisspeptin is involved in the regulation of endocrine function and the onset of puberty, with activation of the kisspeptin receptor triggering release of gonadotropin-releasing hormone (GnRH), and release of kisspeptin itself being inhibited by oestradiol but enhanced by GnRH. Reductions in kisspeptin levels with age may conversely be one of the reasons behind age-related declines in levels of other endocrine hormones such as luteinizing hormone.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | R257Hu01 | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | MR257Hu21 | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| PR257Hu01 | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | KER257Hu | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | R257Mu01 | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| PR257Mu01 | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | KER257Mu | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | R257Ra01 | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | MR257Ra21 | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| PR257Ra01 | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | KER257Ra | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Kisspeptin Receptor (KISS1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Kisspeptin Receptor (KISS1R) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Kisspeptin Receptor (KISS1R) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Kisspeptin Receptor (KISS1R) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Kisspeptin Receptor (KISS1R) | CLIA assay for Antigen Detection |
Reference
"Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor."
Nature 411:613-617(2001) [PubMed] [Europe PMC] [Abstract]
"FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54."
Biochem. Biophys. Res. Commun. 284:1189-1193(2001) [PubMed] [Europe PMC] [Abstract]
"AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1."
J. Biol. Chem. 276:28969-28975(2001) [PubMed] [Europe PMC] [Abstract]
"The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54."
J. Biol. Chem. 276:34631-34636(2001) [PubMed] [Europe PMC] [Abstract]
"The GPR54 gene as a regulator of puberty."
N. Engl. J. Med. 349:1614-1627(2003) [PubMed] [Europe PMC] [Abstract]
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Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
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Trends Endocrinol. Metab. 15:448-453(2004) [PubMed] [Europe PMC] [Abstract]
"Metastin suppresses the motility and growth of CHO cells transfected with its receptor."
Biochem. Biophys. Res. Commun. 286:958-963(2001) [PubMed] [Europe PMC] [Abstract]
"Transcriptional expression of genes involved in cell invasion and migration by normal and tumoral trophoblast cells."
J. Clin. Endocrinol. Metab. 87:5336-5339(2002) [PubMed] [Europe PMC] [Abstract]
"Metastin receptor is overexpressed in papillary thyroid cancer and activates MAP kinase in thyroid cancer cells."
J. Clin. Endocrinol. Metab. 87:2399-2399(2002) [PubMed] [Europe PMC] [Abstract]
"Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54."
Proc. Natl. Acad. Sci. U.S.A. 100:10972-10976(2003) [PubMed] [Europe PMC] [Abstract]
"Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in hepatocellular carcinoma."
J. Cancer Res. Clin. Oncol. 129:531-535(2003) [PubMed] [Europe PMC] [Abstract]
"Clinical significance of the loss of KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in esophageal squamous cell carcinoma."
Clin. Cancer Res. 10:1379-1383(2004) [PubMed] [Europe PMC] [Abstract]
"Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts."
J. Cell Sci. 117:1319-1328(2004) [PubMed] [Europe PMC] [Abstract]
"Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other G(q)-coupled receptors."
Biochem. Biophys. Res. Commun. 326:677-686(2005) [PubMed] [Europe PMC] [Abstract]
"Two novel missense mutations in G protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism."
J. Clin. Endocrinol. Metab. 90:1849-1855(2005) [PubMed] [Europe PMC] [Abstract]
"Neuroendocrine phenotype analysis in five patients with isolated hypogonadotropic hypogonadism due to a L102P inactivating mutation of GPR54."
J. Clin. Endocrinol. Metab. 92:1137-1144(2007) [PubMed] [Europe PMC] [Abstract]
"A GPR54-activating mutation in a patient with central precocious puberty."
N. Engl. J. Med. 358:709-715(2008) [PubMed] [Europe PMC] [Abstract]
"Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism."
Am. J. Hum. Genet. 92:725-743(2013) [PubMed] [Europe PMC] [Abstract]
"The prevalence of CHD7 missense versus truncating mutations is higher in patients with Kallmann syndrome than in typical CHARGE patients."
J. Clin. Endocrinol. Metab. 99:E2138-2143(2014) [PubMed] [Europe PMC] [Abstract]