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Multimerin 2 (MMRN2)

EMILIN3; EndoGlyx-1; Elastin Microfibril Interfacer 3; Elastin microfibril interface located protein 3; EndoGlyx-1 p125/p140 subunit

ENDOGLYX1, a 500-kD cell surface glycoprotein complex, and sequenced peptides derived from the component proteins. By searching databases using the peptide sequences, they obtained a full-length cDNA encoding MMRN2, which they called ENDOGLYX1. The deduced 949-amino acid protein has a calculated molecular mass of 104.4 kD. It contains an N-terminal signal sequence, followed by 2 major globular domains, an emilin (EM1) domain and a C-terminal C1q -like domain, which are separated by a large central coiled-coil-rich region. The EM1 domain contains 7 cysteines, 6 of which likely form disulfide bridges. The coiled-coil-rich region is divided into coiled-coil subdomains interrupted by noncoiled regions, allowing structural flexibility. An acidic region precedes the C1q region and is typically found in proteins that interact with glycosaminoglycans.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R201Hu01 Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies MR201Hu21 Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
PR201Hu01 Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits KER201Hu ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R201Mu01 Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
PR201Mu01 Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits KER201Mu ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Multimerin 2 (MMRN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Multimerin 2 (MMRN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Multimerin 2 (MMRN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Multimerin 2 (MMRN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Multimerin 2 (MMRN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Multimerin 2 (MMRN2) CLIA assay for Antigen Detection

Reference

"Molecular cloning and characterization of EndoGlyx-1, an EMILIN-like multisubunit glycoprotein of vascular endothelium."
J. Biol. Chem. 276:48588-48595(2001) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

"MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway."
Oncogene 31:3136-3147(2012) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]