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Anoctamin 2 (ANO2)
Anoctamin 2 (ANO2)
TMEM16B; C12orf3; Transmembrane Protein 16B(Eight Membrane-Spanning Domains)
By database searching with the sequence of TMEM16A as query, Katoh and Katoh (2003) identified TMEM16B. The deduced 999-amino acid TMEM16B protein shares 58.4% sequence identity with TMEM16A. Like TMEM16A, TMEM16B contains 8 potential transmembrane regions with the N- and C-terminal tails facing the cytoplasm and an N-linked glycosylation site in the fourth extracellular loop.
By sequence analysis, Katoh and Katoh (2003) mapped the TMEM16B gene to chromosome 12p13.Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina.Retina, especially in the photoreceptor synaptic terminals.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
R011Hu01
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
PR011Hu01
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Anoctamin 2 (ANO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Anoctamin 2 (ANO2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Anoctamin 2 (ANO2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Anoctamin 2 (ANO2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Anoctamin 2 (ANO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Anoctamin 2 (ANO2) CLIA assay for Antigen Detection
Reference
"TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals." J. Neurosci. 29:6809-6818(2009) [PubMed ] [Europe PMC ] [Abstract ]
"The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Expression and function of epithelial anoctamins." J. Biol. Chem. 285:7838-7845(2010) [PubMed ] [Europe PMC ] [Abstract ]
"Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?" Acta Pharmacol. Sin. 32:685-692(2011) [PubMed ] [Europe PMC ] [Abstract ]
"Anoctamins." Pflugers Arch. 462:195-208(2011) [PubMed ] [Europe PMC ] [Abstract ]
"The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age." Exp. Physiol. 97:175-176(2012) [PubMed ] [Europe PMC ] [Abstract ]
"The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels." Exp. Physiol. 97:177-183(2012) [PubMed ] [Europe PMC ] [Abstract ]
"Anoctamin 2/TMEM16B: a calcium-activated chloride channel in olfactory transduction." Exp. Physiol. 97:193-199(2012) [PubMed ] [Europe PMC ] [Abstract ]
