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Anoctamin 6 (ANO6)

TMEM16F; SCAN channel; Transmembrane Protein 16F; Small-conductance calcium-activated nonselective cation channel

By searching databases for sequences similar to TMEM16A, Katoh and Katoh (2004) identified TMEM16F. The deduced 892-amino acid protein contains 8 transmembrane domains. The N and C termini are cytoplasmic, and the extracellular regions contain 6 putative N-glycosylation sites. TMEM16F and TMEM16E share 50.3% amino acid identity. By EST database analysis, Katoh and Katoh (2004) determined that TMEM16F is expressed in embryonic stem cells, fetal liver, retina, chronic myelogenous leukemia, and intestinal cancer.Katoh and Katoh (2004) determined that the TMEM16F gene contains 20 exons and spans more than 119.7 kb.This locus is paralogous to the NELL1-TMEM16E locus on chromosome 11p15.1-p14.3. Katoh and Katoh (2004) also mapped the mouse Tmem16f gene to chromosome 15E3.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins Q994Hu01 Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies MQ994Hu21 Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
PQ994Hu01 Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits KEQ994Hu ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Anoctamin 6 (ANO6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Anoctamin 6 (ANO6) Bioactivity
Antibodies NONE Monoclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Anoctamin 6 (ANO6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Anoctamin 6 (ANO6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Anoctamin 6 (ANO6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Anoctamin 6 (ANO6) CLIA assay for Antigen Detection

Reference

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"Identification and characterization of TMEM16E and TMEM16F genes in silico."
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"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
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Nature 468:834-838(2010) [PubMed] [Europe PMC] [Abstract]

"Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?"
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"Anoctamins."
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"Anoctamin 6 is an essential component of the outwardly rectifying chloride channel."
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"ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins."
Am. J. Physiol. 302:C482-C493(2012) [PubMed] [Europe PMC] [Abstract]

"The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age."
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"The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels."
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"Expression and function of epithelial anoctamins."
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"Anoctamins are a family of Ca2+ activated Cl- channels."
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"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
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