Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1)
VR1; OTRPC1; Vanilloid Receptor Subtype 1; Capsaicin receptor; Osm-9-like TRP channel 1; Vanilloid receptor 1
TRPV1 is a nonselective cation channel that may be activated by a wide variety of exogenous and endogenous physical and chemical stimuli. The best-known activators of TRPV1 are heat greater than 43°C and capsaicin, the pungent compound in hot chili peppers.
The activation of TRPV1 leads to painful, burning sensation. Its endogenous activators include: low pH, the endocannabinoid anandamide, N-arachidonoyl-dopamine. TRPV1 receptors are found mainly in the nociceptive neurons of the peripheral nervous system, but they have also been described in many other tissues, including the central nervous system. TRPV1 is involved in the transmission and modulation of pain, as well as the integration of diverse painful stimuli.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Hu01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Hu01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Hu01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Hu01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Hu01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Mu01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Mu01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Mu01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Mu01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Mu01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Ra01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Ra01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Ra01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Ra01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Ra01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Ca01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Ca01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Ca01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Ca01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Ca01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Po01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Po01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Po01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Po01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Po01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Bo01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Bo01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Bo01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Bo01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Bo01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Rb01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Rb01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Rb01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Rb01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Rb01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ967Mo01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ967Mo01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IP. |
| PAQ967Mo01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ967Mo01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | CLIA assay for Antigen Detection |
| ELQ967Mo01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning and functional expression of a human orthologue of rat vanilloid receptor-1."
Pain 88:205-215(2000) [PubMed] [Europe PMC] [Abstract]
"The tissue distribution and functional characterization of human VR1."
Biochem. Biophys. Res. Commun. 281:1183-1189(2001) [PubMed] [Europe PMC] [Abstract]
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Br. J. Pharmacol. 132:1084-1094(2001) [PubMed] [Europe PMC] [Abstract]
"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"TRPV3 is a temperature-sensitive vanilloid receptor-like protein."
Nature 418:186-190(2002) [PubMed] [Europe PMC] [Abstract]
"Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures."
Exp. Dermatol. 13:129-139(2004) [PubMed] [Europe PMC] [Abstract]
"Molecular determinants of vanilloid sensitivity in TRPV1."
J. Biol. Chem. 279:20283-20295(2004) [PubMed] [Europe PMC] [Abstract]