Septin 8 (SEPT8)
SEPT8 is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking.
A conserved region found in all 3 variants contains the GTP-binding motif and is encoded by exons 3 through 10. Northern blot analysis detected expression of most SEPT8 variants in all brain and cardiovascular regions tested, as well as in prostate, testis, and ovary. Expression was highest in brain and aorta, and expression of each variant was tissue specific. Western blot analysis detected variant 1 at an apparent molecular mass of 58 kD in prostate, testis, and ovary.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEQ938Hu | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Septin 8 (SEPT8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Septin 8 (SEPT8) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Septin 8 (SEPT8) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Septin 8 (SEPT8) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Septin 8 (SEPT8) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Septin 8 (SEPT8) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Septin 8 (SEPT8) | CLIA assay for Antigen Detection |
Reference
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FEBS Lett. 519:169-172(2002) [PubMed] [Europe PMC] [Abstract]
"Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202)."
Gene 312:313-320(2003) [PubMed] [Europe PMC] [Abstract]
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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Mol. Biol. Cell 13:4111-4113(2002) [PubMed] [Europe PMC] [Abstract]
"KIAA0202, a human septin family member, interacting with hPFTAIRE1."
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34:520-525(2002) [PubMed] [Europe PMC] [Abstract]
"The novel human platelet septin SEPT8 is an interaction partner of SEPT4."
Thromb. Haemost. 91:959-966(2004) [PubMed] [Europe PMC] [Abstract]
"Expression profiling the human septin gene family."
J. Pathol. 206:269-278(2005) [PubMed] [Europe PMC] [Abstract]
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Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
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J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]