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Dual Specificity Phosphatase 5 (DUSP5)

DUSP; HVH3; Dual specificity protein phosphatase hVH3

DUSP5 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins Q828Hu01 Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies MQ828Hu21 Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
PQ828Hu01 Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits KEQ828Hu ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins Q828Mu01 Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
PQ828Mu01 Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits KEQ828Mu ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dual Specificity Phosphatase 5 (DUSP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dual Specificity Phosphatase 5 (DUSP5) Bioactivity
Antibodies NONE Monoclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dual Specificity Phosphatase 5 (DUSP5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dual Specificity Phosphatase 5 (DUSP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dual Specificity Phosphatase 5 (DUSP5) CLIA assay for Antigen Detection

Reference

"A novel dual specificity phosphatase induced by serum stimulation and heat shock."
J. Biol. Chem. 269:29897-29902(1994) [PubMed] [Europe PMC] [Abstract]

"Multiple dual specificity protein tyrosine phosphatases are expressed and regulated differentially in liver cell lines."
J. Biol. Chem. 270:1156-1160(1995) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase."
Proteins 66:253-258(2007) [PubMed] [Europe PMC] [Abstract]