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N-Acetyltransferase 2 (NAT2)

AAC2; PNAT; Arylamine N-Acetyltransferase; Arylamide acetylase 2; Polymorphic arylamine N-acetyltransferase

NAT2 isa type of N-acetyltransferase. The NAT2 isozyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.
NAT2 encodes the polymorphic NAT protein because the gene product had an identical apparent molecular weight to that of NAT detected in human liver cytosol and the deduced amino acid sequence of NAT2 contained 6 peptide sequences that had previously been determined from tryptic peptides of the polymorphic NAT purified from human liver.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins Q613Ra01 Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies MQ613Ra21 Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
PQ613Ra01 Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits KEQ613Ra ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant N-Acetyltransferase 2 (NAT2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native N-Acetyltransferase 2 (NAT2) Bioactivity
Antibodies NONE Monoclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to N-Acetyltransferase 2 (NAT2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for N-Acetyltransferase 2 (NAT2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for N-Acetyltransferase 2 (NAT2) CLIA assay for Antigen Detection

Reference

"Nucleotide sequence of an intronless gene for a human arylamine N-acetyltransferase related to polymorphic drug acetylation."
Nucleic Acids Res. 17:3978-3978(1989) [PubMed] [Europe PMC] [Abstract]

"Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression."
DNA Cell Biol. 9:193-203(1990) [PubMed] [Europe PMC] [Abstract]

"Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver."
J. Biol. Chem. 265:4630-4634(1990) [PubMed] [Europe PMC] [Abstract]

"Sequences and expression of alleles of polymorphic arylamine N-acetyltransferase of human liver."
J. Biol. Chem. 267:18140-18147(1992) [PubMed] [Europe PMC] [Abstract]

"Cloning, expression, and functional characterization of two mutant (NAT2(191) and NAT2(341/803)) and wild-type human polymorphic N-acetyltransferase (NAT2) alleles."
Drug Metab. Dispos. 22:371-376(1994) [PubMed] [Europe PMC] [Abstract]

"Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes."
Am. J. Hum. Genet. 78:423-436(2006) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferases."
Biochem. Biophys. Res. Commun. 177:1252-1257(1991) [PubMed] [Europe PMC] [Abstract]

"Evidence for two closely related isozymes of arylamine N-acetyltransferase in human liver."
FEBS Lett. 244:203-207(1989) [PubMed] [Europe PMC] [Abstract]

"Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases."
J. Biol. Chem. 282:30189-30197(2007) [PubMed] [Europe PMC] [Abstract]

"Diverse point mutations in the human gene for polymorphic N-acetyltransferase."
Proc. Natl. Acad. Sci. U.S.A. 88:6333-6337(1991) [PubMed] [Europe PMC] [Abstract]

"The structure and characteristics of a fourth allele of polymorphic N-acetyltransferase gene found in the Japanese population."
Biochem. Biophys. Res. Commun. 191:811-816(1993) [PubMed] [Europe PMC] [Abstract]

"Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene."
Pharmacogenetics 4:125-134(1994) [PubMed] [Europe PMC] [Abstract]