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Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)

BDGI; OKL38; Bone Marrow Stromal Cell-Derived Growth Inhibitor; Pregnancy Induced Growth Inhibitor; Ovary, kidney and liver protein 38

The deduced 317-amino acid protein has a calculated molecular mass of about 34.5 kD. OKL38 does not have a transmembrane domain or signal peptide. Minor transcripts of 3.6 and 4.0 kb were also observed.
In situ hybridization detected Okl38 in undifferentiated mammary epithelial cells of nonpregnant rats, and expression was upregulated in secretory epithelial of 18-day pregnant rats. Northern blot analysis detected reduced OKL38 expression in human breast cancer cell lines compared with normal mammary tissue. Expression was also reduced in chemically-induced rat mammary tumors. Overexpression of OKL38 in a human breast cancer cell line reduced the ability of these cells to form tumors in nude mice.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Hu01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Hu01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Hu01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Hu01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Hu01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Mu01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Mu01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Mu01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Mu01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Mu01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Ra01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Ra01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Ra01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Ra01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Ra01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Ca01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Ca01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Ca01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Ca01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Ca01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Po01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Po01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Po01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Po01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Po01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Bo01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Bo01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Bo01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Bo01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Bo01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Rb01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Rb01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Rb01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Rb01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Rb01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ605Mo01 Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ605Mo01 Monoclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IP.
PAQ605Mo01 Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) WB; IHC; ICC; IF.
Assay Kits CLQ605Mo01 CLIA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA assay for Antigen Detection
ELQ605Mo01 ELISA Kit for Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Genomic structure of human OKL38 gene and its differential expression in kidney carcinogenesis."
J. Biol. Chem. 279:743-754(2004) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The sequence and analysis of duplication-rich human chromosome 16."
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Cloning and characterization of a novel pregnancy-induced growth inhibitor in mammary gland."
Endocrinology 142:3607-3615(2001) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]