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Channel Activating Protease 1 (CAP1)
Channel Activating Protease 1 (CAP1)
PRSS8; Prostasin; Protease, Serine 8
PRSS8 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The 3-prime end of the cDNA was obtained by the RACE method. A 1.8-kb cDNA sequence was assembled encoding a predicted protein of 343 amino acids which contains a 32-amino acid signal peptide. The protein, designated serine protease-8 (PRSS8), was called prostasin by the authors. The precursor, proprostasin, is cleaved between residues 12 and 13 to produce a 12-amino acid light chain and a 299-amino acid heavy chain which are associated through a disulfide bond. The predicted amino acid sequence is between 34 and 42% identical to human acrosin, plasma kallikrein, and hepsin.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
Q491Hu01
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
MQ491Hu21
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
PQ491Hu01
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
KEQ491Hu
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
PQ491Mu01
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
PQ491Ra01
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
LQ491Ra71
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
LQ491Ra81
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Channel Activating Protease 1 (CAP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Channel Activating Protease 1 (CAP1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Channel Activating Protease 1 (CAP1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Channel Activating Protease 1 (CAP1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Channel Activating Protease 1 (CAP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Channel Activating Protease 1 (CAP1) CLIA assay for Antigen Detection
Reference
"Molecular cloning, tissue-specific expression, and cellular localization of human prostasin mRNA." J. Biol. Chem. 270:13483-13489(1995) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland." PubMed ] [Europe PMC ] [Abstract ]
"Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line." Am. J. Physiol. 287:L928-L935(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Biochemical characterization of prostasin, a channel activating protease." Biochem. Biophys. Res. Commun. 324:953-963(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations." Protein Sci. 18:1081-1094(2009) [PubMed ] [Europe PMC ] [Abstract ]
