ATPase, Na+/K+ Transporting Beta 1 Polypeptide (ATP1b1)

ATP1B; Sodium/potassium-dependent ATPase subunit beta-1

SPN	Q440
HGNC	804
MGI	88108
PubMed	23048038
RGD	2170
UniProt	P05026
Wiki	ATP1B1

ATP1b1 belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes.

Reference

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