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Betaine Homocysteine Methyltransferase (BHMT)
Betaine Homocysteine Methyltransferase (BHMT)
Betaine—homocysteine S-methyltransferase
Betaine-homocysteine methyltransferase (BHMT; EC 2.1.1.5) is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. The sequence of the predicted 406-amino acid human BHMT is 94% identical to that of the porcine protein.Maximal expression was observed when rats consumed diets deficient in methionine yet rich in methyl donors, such as choline, betaine, or sulfonium analogs of betaine.BHMT2 was rapidly degraded when translated in vitro in rabbit reticulocyte lysates. BHMT2 was stabilized by cotransfection of COS-1 cells with BHMT, and after cotransfection, BHMT2 coprecipitated with BHMT.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Betaine Homocysteine Methyltransferase (BHMT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Betaine Homocysteine Methyltransferase (BHMT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Betaine Homocysteine Methyltransferase (BHMT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Betaine Homocysteine Methyltransferase (BHMT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Betaine Homocysteine Methyltransferase (BHMT) CLIA assay for Antigen Detection
Reference
"Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase." PubMed ] [Europe PMC ] [Abstract ]
"Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene." J. Biol. Chem. 274:7816-7824(1999) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene." Arch. Biochem. Biophys. 345:171-174(1997) [PubMed ] [Europe PMC ] [Abstract ]
"Human betaine-homocysteine methyltransferase is a zinc metalloenzyme." Arch. Biochem. Biophys. 356:93-98(1998) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
"Betaine-homocysteine methyltransferase: zinc in a distorted barrel." Structure 10:1159-1171(2002) [PubMed ] [Europe PMC ] [Abstract ]
"Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease." Atherosclerosis 167:205-214(2003) [PubMed ] [Europe PMC ] [Abstract ]
