RNA Binding Motif Protein 38 (RBM38)

HSRNASEB; SEB4D; Seb4B; RNPC1; RNA-Binding Region(RNP1,RRM)Containing 1; CLL-associated antigen KW-5; ssDNA-binding protein SEB4

SPN	Q155
HGNC	15818
MGI	1889294
PubMed	22027593
RGD	1308503
UniProt	Q9H0Z9

Using microarray analysis to identify potential p53 (TP53) target genes in human cell lines, Shu et al. (2006) identified and cloned 2 variants of RBM38, which they called RNPC1a and RNPC1b. The deduced proteins contain 239 and 121 amino acids, respectively, and both contain an identical N-terminal canonical RNA recognition motif made up of 2 conserved submotifs, RNP1 and RNP2. Immunofluorescence analysis localized both proteins in the perinuclear membrane and cytosol, with a larger proportion of RNPC1b localized to the cytosol than the nucleus.Both RNPC1a and RNPC1b were also induced by several p63 (TP63) and p73 (TP73) isoforms. RNPC1 expression was induced by DNA-damaging agents in cells expressing wildtype p53, but not in cells lacking p53 expression.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Hu01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Hu01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Hu01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Hu01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Hu01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Mu01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Mu01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Mu01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Mu01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Mu01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Ra01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Ra01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Ra01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Ra01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Ra01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Ca01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Ca01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Ca01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Ca01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Ca01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Po01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Po01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Po01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Po01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Po01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Bo01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Bo01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Bo01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Bo01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Bo01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Rb01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Rb01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Rb01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Rb01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Rb01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ155Mo01	Recombinant RNA Binding Motif Protein 38 (RBM38)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ155Mo01	Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IP.
Antibodies	PAQ155Mo01	Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38)	WB; IHC; ICC; IF.
Assay Kits	CLQ155Mo01	CLIA Kit for RNA Binding Motif Protein 38 (RBM38)	CLIA assay for Antigen Detection
Assay Kits	ELQ155Mo01	ELISA Kit for RNA Binding Motif Protein 38 (RBM38)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX."
Blood 100:2123-2131(2002) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 20."
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript."
Genes Dev. 20:2961-2972(2006) [PubMed] [Europe PMC] [Abstract]

"ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing."
Mol. Cell 33:591-601(2009) [PubMed] [Europe PMC] [Abstract]

"Solution structure of the RNA recognition motif in RNA-binding region containing protein 1."
Submitted (MAY-2005) to the PDB data bank