Meprin A Beta (MEP1b)
PPH Beta; Endopeptidase-2; Meprin B; PABA Peptide Hydrolase; N-benzoyl-L-tyrosyl-P-amino-Benzoic Acid Hydrolase Subunit Beta
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha (MEP1A) are secreted; oligomers containing meprin-beta are associated with the plasma membrane.
Mep1b-null mice were born at half the expected mendelian ratio, but those that survived developed normally and were viable and fertile. Mutant mice lacked membrane-associated Mep1a in kidney and intestine, and microarray analysis indicated that renal gene expression profiles were different than those of wildtype mice.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | P898Hu01 | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | MP898Hu21 | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| PP898Hu01 | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEP898Hu | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | P898Ra01 | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| PP898Ra01 | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Meprin A Beta (MEP1b) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Meprin A Beta (MEP1b) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Meprin A Beta (MEP1b) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Meprin A Beta (MEP1b) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Meprin A Beta (MEP1b) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Meprin A Beta (MEP1b) | CLIA assay for Antigen Detection |
Reference
"Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin) alpha and beta subunits in Madin-Darby canine kidney cells."
Eur. J. Biochem. 247:920-932(1997) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells."
FEBS Lett. 335:367-375(1993) [PubMed] [Europe PMC] [Abstract]
"N-Benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase beta (human meprinbeta). A 13-amino-acid sequence is required for proteolytic processing and subsequent secretion."
Eur. J. Biochem. 261:421-429(1999) [PubMed] [Europe PMC] [Abstract]
"Human meprin beta: O-linked glycans in the intervening region of the type I membrane protein protect the C-terminal region from proteolytic cleavage and diminish its secretion."
Biochem. J. 369:659-665(2003) [PubMed] [Europe PMC] [Abstract]
"Critical amino acids in the active site of meprin metalloproteinases for substrate and peptide bond specificity."
J. Biol. Chem. 278:42545-42550(2003) [PubMed] [Europe PMC] [Abstract]
"Prointerleukin-18 is activated by meprin beta in vitro and in vivo in intestinal inflammation."
J. Biol. Chem. 283:31371-31377(2008) [PubMed] [Europe PMC] [Abstract]
"The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion."
PLoS ONE 3:E2153-E2153(2008) [PubMed] [Europe PMC] [Abstract]
"Fetuin-A and cystatin C are endogenous inhibitors of human meprin metalloproteases."
Biochemistry 49:8599-8607(2010) [PubMed] [Europe PMC] [Abstract]
"Specific processing of tenascin-C by the metalloprotease meprinbeta neutralizes its inhibition of cell spreading."
Matrix Biol. 29:31-42(2010) [PubMed] [Europe PMC] [Abstract]
"Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates."
Mol. Cell. Proteomics 10:M111.009233.01-M111.009233.19(2011) [PubMed] [Europe PMC] [Abstract]
"The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin beta and ADAM10."
Cell. Mol. Life Sci. 70:309-333(2013) [PubMed] [Europe PMC] [Abstract]
"Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane."
Proc. Natl. Acad. Sci. U.S.A. 109:16131-16136(2012) [PubMed] [Europe PMC] [Abstract]
"Diagnostic exome sequencing in persons with severe intellectual disability."
N. Engl. J. Med. 367:1921-1929(2012) [PubMed] [Europe PMC] [Abstract]