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Cold Inducible RNA Binding Protein (CIRBP)
Cold Inducible RNA Binding Protein (CIRBP)
CIRP; A18HNRNP; Glycine-Rich RNA Binding Protein
Cold stress induces in microorganisms the synthesis of several proteins that are involved in various cellular processes such as transcription, translation, and recombination. The cold-inducible RNA-binding protein (Cirp) is induced in rodent cells by mild cold stress (32 degrees C). Cirp consists of an N-terminal RNA-binding domain and a C-terminal gly-rich domain, and plays an essential role in cold-induced suppression of cell proliferation.
CIRBP mRNA was constitutively expressed in all cell lines examined. In all of the cell lines, the levels of CIRBP mRNA and protein were increased within 12 hours after a temperature downshift from 37 degrees C to 32 degrees C. These results demonstrated that CIRBP is a cold-shock protein in human cells.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
P860Mu01
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
KEP860Ra
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cold Inducible RNA Binding Protein (CIRBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cold Inducible RNA Binding Protein (CIRBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cold Inducible RNA Binding Protein (CIRBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cold Inducible RNA Binding Protein (CIRBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cold Inducible RNA Binding Protein (CIRBP) CLIA assay for Antigen Detection
Reference
"Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene." Gene 204:115-120(1997) [PubMed ] [Europe PMC ] [Abstract ]
"Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein." J. Biol. Chem. 272:26720-26726(1997) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The UV-inducible RNA-binding protein A18 (A18 hnRNP) plays a protective role in the genotoxic stress response." J. Biol. Chem. 276:47277-47284(2001) [PubMed ] [Europe PMC ] [Abstract ]
"Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism." J. Cell Sci. 117:1785-1794(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Post-transcriptional regulation of thioredoxin by the stress inducible heterogeneous ribonucleoprotein A18." Nucleic Acids Res. 34:1224-1236(2006) [PubMed ] [Europe PMC ] [Abstract ]
"A quantitative atlas of mitotic phosphorylation." Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed ] [Europe PMC ] [Abstract ]
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Sci. Signal. 2:RA46-RA46(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
"Solution structure of RRM domain in A18 HNRNP." Submitted (NOV-2005) to the PDB data bank