Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2)
QCR2; UQCR2; Cytochrome b-c1 complex subunit 2, mitochondrial; Complex III subunit 2; Core protein II
The amount of PPARG, PPARG coactivator-1-alpha (PPARGC1A), ubiquinol-cytochrome c oxidoreductase core 2 subunit (UQCRC2), cytochrome c oxidase subunit I (MTCO1), uncoupling protein-2 (UCP2), and ATP synthase H(+)-transporting mitochondrial F1 complex (F1-ATP synthase) were markedly reduced in the low capacity runner rats in comparison with the high capacity runners.
The uniform decline in these proteins was consistent with the hypothesis that reduced aerobic metabolism plays a causal role in the development of the differences between the low capacity runner and high capacity runner rats. impairment of mitochondrial function may link reduced fitness to cardiovascular and metabolic disease.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Hu01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Hu01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Hu01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Hu01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Hu01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Mu01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Mu01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Mu01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Mu01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Mu01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Ra01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Ra01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Ra01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Ra01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Ra01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Ca01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Ca01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Ca01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Ca01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Ca01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Po01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Po01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Po01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Po01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Po01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Bo01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Bo01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Bo01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Bo01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Bo01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Rb01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Rb01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Rb01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Rb01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Rb01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP830Mo01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP830Mo01 | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAP830Mo01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP830Mo01 | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA assay for Antigen Detection |
| ELP830Mo01 | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Complementary DNA encoding core protein II of human mitochondrial cytochrome bc1 complex. Substantial diversity in deduced primary structure from its yeast counterpart."
J. Biol. Chem. 264:13483-13488(1989) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
, Submitted (MAR-2007) to UniProtKB
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
"Mitochondrial complex III deficiency caused by a homozygous UQCRC2 mutation presenting with neonatal-onset recurrent metabolic decompensation."
Hum. Mutat. 34:446-452(2013) [PubMed] [Europe PMC] [Abstract]