Tumor Protein, Translationally Controlled 1 (TPT1)
HRF; TCTP; p02; p23; Fortilin; Translationally-Controlled Tumor Protein; Histamine-releasing factor
TCTP, is an essential component of the tuberous sclerosis-RHEB pathway. Reducing Drosophila Tctp levels reduced cell size, cell number, and organ size, which mimics Drosophila Rheb mutant phenotypes. Drosophila Tctp is genetically epistatic to Tsc1 and Rheb, but acts upstream of S6K, a downstream target of Rheb. Drosophila Tctp directly associated with Rheb and displayed guanine nucleotide exchange activity with it in vivo and in vitro. Human TCTP showed similar biochemical properties compared to Drosophila Tctp and could rescue Drosophila Tctp mutant phenotypes, suggesting that the function of TCTP in the TSC pathway is evolutionarily conserved. Overexpression of TSAP6 increased the level of TPT1 in exosome preparations and consistently enhanced TPT1 secretion.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Hu01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Hu01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Hu01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Hu01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Hu01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Mu01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Mu01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Mu01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Mu01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Mu01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Ra01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Ra01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Ra01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Ra01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Ra01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Ca01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Ca01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Ca01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Ca01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Ca01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Po01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Po01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Po01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Po01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Po01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Bo01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Bo01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Bo01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Bo01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Bo01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Rb01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Rb01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Rb01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Rb01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Rb01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP739Mo01 | Recombinant Tumor Protein, Translationally Controlled 1 (TPT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP739Mo01 | Monoclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IP. |
| PAP739Mo01 | Polyclonal Antibody to Tumor Protein, Translationally Controlled 1 (TPT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP739Mo01 | CLIA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | CLIA assay for Antigen Detection |
| ELP739Mo01 | ELISA Kit for Tumor Protein, Translationally Controlled 1 (TPT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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