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Sulfatase 1 (SULF1)
Sulfatase 1 (SULF1)
HSULF-1; Extracellular sulfatase Sulf-1
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
The deduced 871-amino acid protein contains an N-terminal signal sequence, followed by a sulfatase domain, a hydrophilic region, and a C-terminal substrate recognition domain. It also has a coiled-coil region, 10 N-glycosylation sites, and several consensus furin cleavage sites. SULF1 shares about 64% identity with SULF2 and 93% identity with mouse Sulf1.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
P635Hu01
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
MP635Hu21
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
PP635Hu01
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
KEP635Hu
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
KCP635Hu
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sulfatase 1 (SULF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sulfatase 1 (SULF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sulfatase 1 (SULF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sulfatase 1 (SULF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sulfatase 1 (SULF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sulfatase 1 (SULF1) CLIA assay for Antigen Detection
Reference
"Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans." J. Biol. Chem. 277:49175-49185(2002) [PubMed ] [Europe PMC ] [Abstract ]
"Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer." J. Biol. Chem. 278:23107-23117(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." DNA Res. 6:197-205(1999) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." J. Proteome Res. 8:651-661(2009) [PubMed ] [Europe PMC ] [Abstract ]
