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STAM Binding Protein (STAMBP)
STAM Binding Protein (STAMBP)
AMSH; Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase
Signal-transducing adaptor molecule (STAM) acts downstream of interleukin-2 (IL2)-induced signaling through JAK3. It also interacts with JAK2 after granulocyte-macrophage colony-stimulating factor (GMCSF) stimulation. STAM contains an SH3 domain that is required for induction of MYC and cell growth.
STAMBP binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.The deduced 424-amino acid protein contains 2 potential SH3-binding domains (PxxP motifs), a JAB1 subdomain homologous (JSH) region, and a putative bipartite nuclear localization signal.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
PP620Hu01
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
PP620Mu01
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant STAM Binding Protein (STAMBP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native STAM Binding Protein (STAMBP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to STAM Binding Protein (STAMBP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to STAM Binding Protein (STAMBP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for STAM Binding Protein (STAMBP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for STAM Binding Protein (STAMBP) CLIA assay for Antigen Detection
Reference
"Possible involvement of a novel STAM-associated molecule 'AMSH' in intracellular signal transduction mediated by cytokines." J. Biol. Chem. 274:19129-19135(1999) [PubMed ] [Europe PMC ] [Abstract ]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Discovery of novel human transcript variants by analysis of intronic single-block EST with polyadenylation site." BMC Genomics 10:518-518(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads." EMBO J. 20:4132-4142(2001) [PubMed ] [Europe PMC ] [Abstract ]
"MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function." BMC Biochem. 3:28-28(2002) [PubMed ] [Europe PMC ] [Abstract ]
"AMSH is an endosome-associated ubiquitin isopeptidase." J. Cell Biol. 166:487-492(2004) [PubMed ] [Europe PMC ] [Abstract ]
"An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein." Oncogene 23:1801-1808(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding." Proc. Natl. Acad. Sci. U.S.A. 103:19140-19145(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation." J. Biol. Chem. 282:9805-9812(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly-capillary malformation syndrome." Nat. Genet. 45:556-562(2013) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]