Sorcin (SRI)
SCN; CP-22; V19; 22 kDa protein
The 22-kD sorcin protein was overexpressed in HOB1/VCR-1.0 cells, a multidrug-resistant human B immunoblastic lymphoma cell line. By PCR with primers based on the sequence of hamster sorcin, the authors recovered a partial human sorcin cDNA. Using the partial cDNA to screen a HOB1/VCR-1.0 library, they isolated cDNAs corresponding to the entire sorcin coding region. The predicted 198-amino acid human protein shares 95% sequence identity with hamster sorcin.
Human sorcin contains 4 EF-hand calcium-binding motifs. Purified protein bound calcium in vitro. Southern and Northern blot analysis revealed that the sorcin gene is amplified and overexpressed in HOB1/VCR-1.0 cells. No expression was detected in parental HOB1 cells.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Hu01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Hu01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Hu01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Hu01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Hu01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Mu01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Mu01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Mu01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Mu01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Mu01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Ra01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Ra01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Ra01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Ra01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Ra01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Ca01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Ca01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Ca01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Ca01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Ca01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Po01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Po01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Po01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Po01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Po01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Bo01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Bo01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Bo01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Bo01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Bo01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Rb01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Rb01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Rb01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Rb01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Rb01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP610Mo01 | Recombinant Sorcin (SRI) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP610Mo01 | Monoclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IP. |
| PAP610Mo01 | Polyclonal Antibody to Sorcin (SRI) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP610Mo01 | CLIA Kit for Sorcin (SRI) | CLIA assay for Antigen Detection |
| ELP610Mo01 | ELISA Kit for Sorcin (SRI) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Isolation and molecular cloning of human sorcin a calcium-binding protein in vincristine-resistant HOB1 lymphoma cells."
Biochim. Biophys. Acta 1260:285-293(1995) [PubMed] [Europe PMC] [Abstract]
"Purification, cDNA cloning, and expression of human sorcin in vincristine-resistant HOB1 lymphoma cell lines."
Arch. Biochem. Biophys. 325:217-226(1996) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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Mamm. Genome 16:942-954(2005) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]