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Sialic Acid Acetylesterase (SIAE)
Sialic Acid Acetylesterase (SIAE)
YSG2; CSE-C; LSE; Sialic Acid-Specific Acetylesterase II; Sialic acid-specific 9-O-acetylesterase
SIAE appears to encode both lysosomal and cytosolic sialic acid acetylesterase isoforms. The deduced 523-amino acid protein has a calculated molecular mass of 58 kD. It contains a putative N-terminal signal sequence and shares significant similarity with mouse Lse. Northern blot analysis detected a 2.7-kb transcript in all tissues examined, with highest expression in testis, prostate, and colon. A 6.0-kb transcript was expressed highly in testis and at lower levels in colon, small intestine, prostate, and thymus. A 7.5-kb transcript was expressed exclusively in colon. In situ hybridization of human embryonic and adult testis detected LSE only in adult testis, where it was restricted to germ cells. Fluorescence-tagged LSE localized to lysosomes in a transfected human pancreatic carcinoma cell line.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Sialic Acid Acetylesterase (SIAE) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Sialic Acid Acetylesterase (SIAE) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Sialic Acid Acetylesterase (SIAE) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Sialic Acid Acetylesterase (SIAE) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Sialic Acid Acetylesterase (SIAE) CLIA assay for Antigen Detection
Reference
"A gene encoding sialic-acid-specific 9-O-acetylesterase found in human adult testis." J. Biomed. Biotechnol. 2004:130-136(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The full-ORF clone resource of the German cDNA consortium." BMC Genomics 8:399-399(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." J. Proteome Res. 8:651-661(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Functionally defective germline variants of sialic acid acetylesterase in autoimmunity." Nature 466:243-247(2010) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
