SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
The deduced 561-residue protein contains an Src homology 2 (SH2) domain, an Src homology 3 (SH3)-binding domain, and a pleckstrin homology domain, suggesting a possible role in signal transduction.
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant SH3 Domain Binding Protein 2 (SH3BP2)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native SH3 Domain Binding Protein 2 (SH3BP2)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to SH3 Domain Binding Protein 2 (SH3BP2)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for SH3 Domain Binding Protein 2 (SH3BP2)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for SH3 Domain Binding Protein 2 (SH3BP2)
CLIA assay for Antigen Detection
Reference
"3BP2 binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase c-FES to the cytoplasmic membrane in a phosphorylation dependent mechanism." Blood 88:473A-473A(1996)
"Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 involved in bladder cancer." Genomics 44:163-170(1997) [PubMed] [Europe PMC] [Abstract]
"The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3." DNA Res. 5:177-186(1998) [PubMed] [Europe PMC] [Abstract]