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Replication Protein A1 (RPA1)

HSSB; REPA1; RF-A; RP-A; RPA70; Replication protein A 70 kDa DNA-binding subunit; Single-stranded DNA-binding protein

SPN P525
HGNC 10289
MGI 1915525
PubMed 21901111
RGD 1307376
UniProt P27694
Wiki RPA1
Replication protein A (RPA) is a 3-subunit single-stranded DNA (ssDNA)-binding protein that has been isolated from human cells and found to be essential for in vitro replication of the papovavirus SV40. The human cDNA directed production in E. coli of a 70-kD protein that reacted with a monoclonal antibody directed against the 70-kD subunit of the human protein. The recombinant subunit, purified from bacteria, exhibited single-stranded DNA-binding activity comparable to that of the complete RPA complex. It could substitute for the complete complex in stimulating the activity of DNA polymerase alpha-primase, but could not substitute for the complete complex in SV40 DNA replication in vitro, suggesting an important functional role for the other subunits.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins P525Hu01 Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies MP525Hu21 Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
PP525Hu01 Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits KEP525Hu ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins P525Ra01 Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies MP525Ra21 Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
PP525Ra01 Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits KEP525Ra ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Protein A1 (RPA1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Protein A1 (RPA1) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Protein A1 (RPA1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Protein A1 (RPA1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Protein A1 (RPA1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Protein A1 (RPA1) CLIA assay for Antigen Detection

Reference

"Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication."
J. Biol. Chem. 266:12090-12098(1991) [PubMed] [Europe PMC] [Abstract]

"Type I human complement C2 deficiency. A 28-base pair gene deletion causes skipping of exon 6 during RNA splicing."
J. Biol. Chem. 268:2268-2268(1993) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

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