p21 Protein Activated Kinase 4 (PAK4)
Serine/threonine-protein kinase PAK 4
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities.
PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Highest expression in prostate, testis and colon.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | MP271Hu21 | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| PP271Hu01 | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEP271Hu | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant p21 Protein Activated Kinase 4 (PAK4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native p21 Protein Activated Kinase 4 (PAK4) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to p21 Protein Activated Kinase 4 (PAK4) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for p21 Protein Activated Kinase 4 (PAK4) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for p21 Protein Activated Kinase 4 (PAK4) | CLIA assay for Antigen Detection |
Reference
"PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia."
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis."
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"P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration."
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"Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4."
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"Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin."
EMBO J. 24:473-486(2005) [PubMed] [Europe PMC] [Abstract]
"PAK4 mediates morphological changes through the regulation of GEF-H1."
J. Cell Sci. 118:1861-1872(2005) [PubMed] [Europe PMC] [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Large-scale proteomics analysis of the human kinome."
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"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
"p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration."
J. Biol. Chem. 285:23699-23710(2010) [PubMed] [Europe PMC] [Abstract]
"Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis."
J. Cell Biol. 190:807-822(2010) [PubMed] [Europe PMC] [Abstract]
"Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B."
Mol. Biol. Cell 21:2996-3006(2010) [PubMed] [Europe PMC] [Abstract]
"p21-activated kinases: three more join the Pak."
Int. J. Biochem. Cell Biol. 34:713-717(2002) [PubMed] [Europe PMC] [Abstract]
"The emerging importance of group II PAKs."
Biochem. J. 425:465-473(2010) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of the human p21-activated kinase 4."
Submitted (JUL-2005) to the PDB data bank
"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]