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NFKB Repressing Factor (NKRF)

ITBA4; NRF; NF-Kappa B Repressing Factor; Transcription factor NRF

NKRF encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.The deduced 388-amino acid protein has a calculated molecular mass of 43.8 kD and contains an N-terminal nuclear localization signal. The C-terminal 92 amino acids of NRF constitute the DNA-binding domain, which has 4 turns and 4 alpha helices, similar to a winged helix-turn-helix DNA-binding motif. Northern blot analysis detected ubiquitous expression of 3.7- and 4.0-kb transcripts that differ in their 3-prime untranslated regions. The longer transcript predominated in most tissues, but the 3.7-kb transcript predominated in brain.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins P200Hu01 Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies MP200Hu21 Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
PP200Hu01 Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits KEP200Hu ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant NFKB Repressing Factor (NKRF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native NFKB Repressing Factor (NKRF) Bioactivity
Antibodies NONE Monoclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to NFKB Repressing Factor (NKRF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to NFKB Repressing Factor (NKRF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for NFKB Repressing Factor (NKRF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for NFKB Repressing Factor (NKRF) CLIA assay for Antigen Detection

Reference

"Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kB-repressing factor), a nuclear inhibitor of NF-kB."
EMBO J. 18:6415-6425(1999) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of a new member (ZNF183) of the Ring finger gene family in Xq24-25."
Gene 192:291-298(1997) [PubMed] [Europe PMC] [Abstract]

"Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: the role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene."
Proc. Natl. Acad. Sci. U.S.A. 99:14212-14217(2002) [PubMed] [Europe PMC] [Abstract]

"Functional proteomic analysis of human nucleolus."
Mol. Biol. Cell 13:4100-4109(2002) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]