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Latexin (LXN)
Latexin (LXN)
ECI; TCI; MUM; Endogenous carboxypeptidase inhibitor; Tissue carboxypeptidase inhibitor
Latexin is a specific inhibitor of zinc-dependent metallocarboxypeptidases. The deduced 222-amino acid protein is an elongated molecule with N- and C-terminal domains that each consist of an alpha helix enveloped by a curved beta sheet. The 2 domains are separated by a connecting segment.Lxn was less potent against other mammalian carboxypeptidases, and it did not inhibit other metallopeptidases or serine proteases.
It also showed low specificity, inhibiting several metallocarboxypeptidases containing a characteristic alpha/beta hydrolase fold. The inhibition constant was within the nanomolar range for these substrates. LXN did not inhibit enzymes of other carboxypeptidase classes.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
P026Hu01
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
PP026Hu01
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
LP026Hu71
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
P026Mu01
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
PP026Mu01
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
LP026Mu71
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
P026Ra01
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
PP026Ra01
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Latexin (LXN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Latexin (LXN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Latexin (LXN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Latexin (LXN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Latexin (LXN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Latexin (LXN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Latexin (LXN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Latexin (LXN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Latexin (LXN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Latexin (LXN) CLIA assay for Antigen Detection
Reference
"Cloning, tissue expression pattern and genomic organization of latexin, a human homologue of rat carboxypeptidase A inhibitor." Mol. Biol. Rep. 27:241-246(2000) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach." Anal. Chem. 81:4493-4501(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin." Proc. Natl. Acad. Sci. U.S.A. 102:3978-3983(2005) [PubMed ] [Europe PMC ] [Abstract ]
