IL2 Inducible T-Cell Kinase (ITK)
PSCTK2; EMT; LYK; T-cell-specific kinase; Tyrosine-protein kinase Lyk
A single 6.2-kb mRNA and 72-kD protein were detected in T lymphocytes and NK-like cell lines, but were not detected in other cell lineages. Sequence comparisons suggested that the protein is probably the human homolog of a murine interleukin-2-inducible T-cell kinase (ITK). However, unlike ITK, the message and protein levels for the new entity did not vary markedly on stimulation of human IL-2 responsive T cells with IL-2. They referred to the gene and its protein product as EMT. They concluded that EMT is a member of a new family of intracellular kinases that includes BPK. The expression of EMT message and protein in thymocytes and mature T cells, combined with its homology to BPK and its chromosomal localization, suggested that EMT may play a role in thymic ontogeny and growth regulation of mature T cells.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | O970Mu01 | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| PO970Mu01 | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| LO970Mu71 | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEO970Mu | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant IL2 Inducible T-Cell Kinase (ITK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native IL2 Inducible T-Cell Kinase (ITK) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to IL2 Inducible T-Cell Kinase (ITK) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for IL2 Inducible T-Cell Kinase (ITK) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for IL2 Inducible T-Cell Kinase (ITK) | CLIA assay for Antigen Detection |
Reference
"A novel human tyrosine kinase gene inducible in T cells by interleukin 2."
FEBS Lett. 324:1-5(1993) [PubMed] [Europe PMC] [Abstract]
"Identification, cloning, and characterization of a novel human T-cell-specific tyrosine kinase located at the hematopoietin complex on chromosome 5q."
Blood 82:1561-1572(1993) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases."
Biochim. Biophys. Acta 1645:123-132(2003) [PubMed] [Europe PMC] [Abstract]
"Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity."
J. Biol. Chem. 272:25401-25408(1997) [PubMed] [Europe PMC] [Abstract]
"CD2-mediated activation of the Tec-family tyrosine kinase ITK is controlled by proline-rich stretch-4 of the CD2 cytoplasmic tail."
Int. Immunol. 10:1009-1016(1998) [PubMed] [Europe PMC] [Abstract]
"Tec kinases: a family with multiple roles in immunity."
Immunity 12:373-382(2000) [PubMed] [Europe PMC] [Abstract]
"Phosphorylation of the linker for activation of T-cells by Itk promotes recruitment of Vav."
Biochemistry 41:10732-10740(2002) [PubMed] [Europe PMC] [Abstract]
"Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor."
J. Immunol. 170:3971-3976(2003) [PubMed] [Europe PMC] [Abstract]
"Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."
Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
"Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk."
Immunity 21:189-201(2004) [PubMed] [Europe PMC] [Abstract]
"Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton."
J. Immunol. 174:1385-1392(2005) [PubMed] [Europe PMC] [Abstract]
"Tec kinase Itk forms membrane clusters specifically in the vicinity of recruiting receptors."
J. Biol. Chem. 281:38529-38534(2006) [PubMed] [Europe PMC] [Abstract]
"Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening."
BMC Immunol. 10:53-53(2009) [PubMed] [Europe PMC] [Abstract]
"SH2-dependent autophosphorylation within the Tec family kinase Itk."
J. Mol. Biol. 391:164-177(2009) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
"Development and validation of a method for profiling post-translational modification activities using protein microarrays."
PLoS ONE 5:E11332-E11332(2010) [PubMed] [Europe PMC] [Abstract]
"Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells."
EMBO J. 30:3160-3172(2011) [PubMed] [Europe PMC] [Abstract]
"Solution structure of the BTK motif and the SH3 domain of tyrosine-protein kinase ITK from human."
Submitted (OCT-2007) to the PDB data bank
"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
"Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation."
J. Clin. Invest. 119:1350-1358(2009) [PubMed] [Europe PMC] [Abstract]