T-Box Protein 3 (TBX3)

TBX3-ISO; UMS; XHL; Ulnar Mammary Syndrome

SPN	O890
HGNC	11602
MGI	98495
PubMed	22865636
RGD	735203
UniProt	O15119
Wiki	TBX3

TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.The complete open reading frame of the TBX3 gene encodes a predicted 723-amino acid protein, of which 255 amino acids are encoded by newly identified exons.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	O890Hu01	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	MO890Hu21	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	PO890Hu01	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	LO890Hu71	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	KEO890Hu	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	O890Mu01	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	PO890Mu01	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	LO890Mu71	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	PO890Ra01	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant T-Box Protein 3 (TBX3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native T-Box Protein 3 (TBX3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to T-Box Protein 3 (TBX3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to T-Box Protein 3 (TBX3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for T-Box Protein 3 (TBX3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for T-Box Protein 3 (TBX3)	CLIA assay for Antigen Detection

Reference

"Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome."
Proc. Natl. Acad. Sci. U.S.A. 96:10212-10217(1999) [PubMed] [Europe PMC] [Abstract]

"Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome."
Nat. Genet. 16:311-315(1997) [PubMed] [Europe PMC] [Abstract]

"The spectrum of mutations in TBX3: genotype/phenotype relationship in ulnar-mammary syndrome."
Am. J. Hum. Genet. 64:1550-1562(1999) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence."
EMBO J. 31:95-109(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome."
Structure 10:343-356(2002) [PubMed] [Europe PMC] [Abstract]