Call Now

FOS Like Antigen 1 (FOSL1)

FRA1

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.
Structure-function analysis demonstrated that the major carboxy-terminal transactivation domains of Fos and FosB are dispensable and that Fosl1, which lacks transactivation domains, has the highest rescue activity. Moreover, a transgene expressing Fosl1 rescued the osteopetrosis of Fos mutant mice in vivo. The osteoclast differentiation factor Rankl induced transcription of Fosl1 in a Fos-dependent manner, thereby establishing a link between Rank signaling and the expression of Ap1 proteins in osteoclast differentiation.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Hu01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Hu01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Hu01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Hu01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Hu01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Mu01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Mu01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Mu01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Mu01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Mu01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Ra01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Ra01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Ra01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Ra01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Ra01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Ca01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Ca01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Ca01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Ca01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Ca01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Po01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Po01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Po01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Po01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Po01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Bo01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Bo01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Bo01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Bo01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Bo01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Rb01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Rb01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Rb01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Rb01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Rb01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO664Mo01 Recombinant FOS Like Antigen 1 (FOSL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO664Mo01 Monoclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IP.
PAO664Mo01 Polyclonal Antibody to FOS Like Antigen 1 (FOSL1) WB; IHC; ICC; IF.
Assay Kits CLO664Mo01 CLIA Kit for FOS Like Antigen 1 (FOSL1) CLIA assay for Antigen Detection
ELO664Mo01 ELISA Kit for FOS Like Antigen 1 (FOSL1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation."
Oncogene 5:249-255(1990) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human T-cell leukemia virus type 1 Tax activates transcription of the human fra-1 gene through multiple cis elements responsive to transmembrane signals."
J. Virol. 67:7001-7007(1993) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]