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Destrin (DSTN)

ADF; ACTDP; Actin Depolymerizing Factor; Actin Binding Protein

Destrin belongs to the actin-binding proteins ADF/cofilin family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
In a variety of eukaryotes, destrin regulates actin in the cytoskeleton. Destrin binds actin and is thought to connect it as gelsolin segment-1 does. Furthermore, the binding of actin by destrin and cofilin is regulated negatively by phosphorylation. Destrin can also sever actin filaments. At a pH of 7.3 or higher it can sever the filaments but a lower pH the ability for it to do so is limited.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins O528Hu01 Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
PO528Hu01 Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits KEO528Hu ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Destrin (DSTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Destrin (DSTN) Bioactivity
Antibodies NONE Monoclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Destrin (DSTN) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Destrin (DSTN) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Destrin (DSTN) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Destrin (DSTN) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Destrin (DSTN) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Destrin (DSTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Destrin (DSTN) CLIA assay for Antigen Detection

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