Diablo Homolog (DIABLO)
SMAC; DIABLO-S; Direct IAP-binding protein with low pI; Second mitochondria-derived activator of caspase
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Hu01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Hu01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Hu01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Hu01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Hu01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Mu01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Mu01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Mu01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Mu01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Mu01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Ra01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Ra01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Ra01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Ra01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Ra01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Ca01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Ca01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Ca01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Ca01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Ca01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Po01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Po01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Po01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Po01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Po01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Bo01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Bo01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Bo01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Bo01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Bo01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Rb01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Rb01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Rb01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Rb01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Rb01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO483Mo01 | Recombinant Diablo Homolog (DIABLO) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO483Mo01 | Monoclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IP. |
| PAO483Mo01 | Polyclonal Antibody to Diablo Homolog (DIABLO) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO483Mo01 | CLIA Kit for Diablo Homolog (DIABLO) | CLIA assay for Antigen Detection |
| ELO483Mo01 | ELISA Kit for Diablo Homolog (DIABLO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition."
Cell 102:33-42(2000) [PubMed] [Europe PMC] [Abstract]
"Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway."
J. Biol. Chem. 275:36152-36157(2000) [PubMed] [Europe PMC] [Abstract]
"Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein."
J. Biol. Chem. 278:52660-52672(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase."
Mol. Cell 14:801-811(2004) [PubMed] [Europe PMC] [Abstract]
"Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway."
Cell Death Differ. 13:2079-2088(2006) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"Survivin monomer plays an essential role in apoptosis regulation."
J. Biol. Chem. 286:23296-23307(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Structural and biochemical basis of apoptotic activation by Smac/DIABLO."
Nature 406:855-862(2000) [PubMed] [Europe PMC] [Abstract]
"Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain."
Nature 408:1004-1008(2000) [PubMed] [Europe PMC] [Abstract]
"Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64."
Am. J. Hum. Genet. 89:56-66(2011) [PubMed] [Europe PMC] [Abstract]