UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2)
HUGT2; UGCGL2; UGT2; UDP-glucose ceramide glucosyltransferase-like 1
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.
By database searching with the HUGT1 sequence, Arnold et al. (2000) identified a homologous sequence, which they designated HUGT2. The assembled full-length HUGT2 cDNA encodes a deduced 1,516-amino acid protein that shares 55% sequence identity with HUGT1. HUGT2 has a predicted ER-targeting signal sequence, a putative ER retrieval signal, and 4 putative N-glycosylation sites. Northern blot analysis detected a 5.1-kb HUGT2 transcript in pancreas, heart, brain, placenta, lung, liver, skeletal muscle, and kidney. Arnold et al. (2000) noted that HUGT1 and HUGT2 differ slightly in their tissue distribution.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Hu01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Hu01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Hu01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Hu01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Hu01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Mu01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Mu01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Mu01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Mu01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Mu01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Ra01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Ra01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Ra01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Ra01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Ra01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Ca01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Ca01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Ca01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Ca01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Ca01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Po01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Po01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Po01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Po01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Po01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Bo01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Bo01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Bo01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Bo01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Bo01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Rb01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Rb01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Rb01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Rb01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Rb01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO481Mo01 | Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO481Mo01 | Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IP. |
| PAO481Mo01 | Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO481Mo01 | CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | CLIA assay for Antigen Detection |
| ELO481Mo01 | ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGGT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity."
Biochemistry 39:2149-2163(2000) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 13."
Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"The noncatalytic portion of human UDP-glucose: glycoprotein glucosyltransferase I confers UDP-glucose binding and transferase function to the catalytic domain."
J. Biol. Chem. 278:43320-43328(2003) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."
PLoS Genet. 9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]