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UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1)

UGTR; HUGT1; GT; UGCGL1; UGGT; UGT1; UDP-glucose ceramide glucosyltransferase-like 1

UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.
The assembled full-length HUGT1 cDNA encodes a deduced 1,555-amino acid protein with a predicted ER-targeting signal sequence, ER retrieval signal, 3 N-glycosylation sites, and 2 disulfide loops. HUGT1 shares 55% sequence identity with HUGT2 and 31 to 45% identity with Drosophila, C. elegans, and S. pombe homologs. Northern blot analysis detected 3 HUGT1 transcripts of 5.7, 8, and 10.6 kb in pancreas, heart, brain, placenta, lung, liver, skeletal muscle, and kidney.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Hu01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Hu01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Hu01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Hu01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Hu01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Mu01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Mu01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Mu01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Mu01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Mu01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Ra01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Ra01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Ra01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Ra01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Ra01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Ca01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Ca01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Ca01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Ca01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Ca01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Po01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Po01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Po01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Po01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Po01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Bo01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Bo01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Bo01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Bo01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Bo01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Rb01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Rb01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Rb01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Rb01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Rb01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO480Mo01 Recombinant UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO480Mo01 Monoclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IP.
PAO480Mo01 Polyclonal Antibody to UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) WB; IHC; ICC; IF.
Assay Kits CLO480Mo01 CLIA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) CLIA assay for Antigen Detection
ELO480Mo01 ELISA Kit for UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity."
Biochemistry 39:2149-2163(2000) [PubMed] [Europe PMC] [Abstract].

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract].

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."
PLoS Genet. 9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]