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Cystatin 1 (CST1)

Cystatin SN; Salivary cystatin-SA-1

SPN O416
HGNC 2473
PubMed 9007972
UniProt P01037
Wiki CST1
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes.
CST1 is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins O416Hu01 Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies MO416Hu21 Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
PO416Hu01 Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
LO416Hu71 Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits KEO416Hu ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cystatin 1 (CST1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cystatin 1 (CST1) Bioactivity
Antibodies NONE Monoclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cystatin 1 (CST1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cystatin 1 (CST1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cystatin 1 (CST1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cystatin 1 (CST1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cystatin 1 (CST1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cystatin 1 (CST1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cystatin 1 (CST1) CLIA assay for Antigen Detection

Reference

"Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family."
Gene 61:329-338(1987) [PubMed] [Europe PMC] [Abstract]

"Purification, molecular cloning, and sequencing of salivary cystatin SA-1."
J. Biol. Chem. 263:9381-9387(1988) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 20."
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Cystatin superfamily. Evidence that family II cystatin genes are evolutionarily related to family III cystatin genes."
Biol. Chem. Hoppe-Seyler 369:191-197(1988) [PubMed] [Europe PMC] [Abstract]

"Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S."
J. Biochem. 110:648-654(1991) [PubMed] [Europe PMC] [Abstract]

"Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting."
Proteomics 2:112-120(2002) [PubMed] [Europe PMC] [Abstract]

"Characterization of a new cysteine proteinase inhibitor of human saliva, cystatin SN, which is immunologically related to cystatin S."
FEBS Lett. 198:145-149(1986) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry."
J. Am. Soc. Mass Spectrom. 21:908-917(2010) [PubMed] [Europe PMC] [Abstract]

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