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Coronin 1A (CORO1A)

CLABP; p57; CLIPINA; HCORO1; TACO; Coronin-1; Coronin,Actin-Binding Protein,1A; Coronin-like protein A; Coronin-like protein p57; Tryptophan aspartate-containing coat protein

The deduced 461-amino acid CORO1A protein shares 40% amino acid identity with coronin, an actin-binding protein of Dictyostelium discoideum. Sequence analysis predicted that CORO1A contains a WD (trp/asp) repeat and a leucine zipper motif. Immunoblot analysis revealed cross-reactivity of human, calf, and mouse CORO1A, and Coro1a was clearly expressed in mouse brain, thymus, spleen, bone marrow, and lymph node, with weak expression in lung and gut, and no expression in liver, kidney, stomach, and skeletal muscle.
CORO1A suppressed Toll-like receptor (TLR) signaling following expression in a human monocytic cell line. TLR2-mediated activation of the innate immune response resulted in suppression of CORO1A expression.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins O392Hu01 Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies MO392Hu21 Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
PO392Hu01 Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits KEO392Hu ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins O392Ra01 Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies MO392Ra21 Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
PO392Ra01 Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits KEO392Ra ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Coronin 1A (CORO1A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Coronin 1A (CORO1A) Bioactivity
Antibodies NONE Monoclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Coronin 1A (CORO1A) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Coronin 1A (CORO1A) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Coronin 1A (CORO1A) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Coronin 1A (CORO1A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Coronin 1A (CORO1A) CLIA assay for Antigen Detection

Reference

"Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif."
FEBS Lett. 364:283-288(1995) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

, Submitted (MAY-2006) to UniProtKB

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
Electrophoresis 13:960-969(1992) [PubMed] [Europe PMC] [Abstract]

"A coat protein on phagosomes involved in the intracellular survival of mycobacteria."
Cell 97:435-447(1999) [PubMed] [Europe PMC] [Abstract]

"Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion."
Clin. Immunol. 131:24-30(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A."
J. Biol. Chem. 286:43465-43474(2011) [PubMed] [Europe PMC] [Abstract]

"Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin."
J. Biol. Chem. 287:42910-42920(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation."
J. Allergy Clin. Immunol. 131:1594-1603(2013) [PubMed] [Europe PMC] [Abstract]