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Adrenomedullin 2 (ADM2)

AM2; IMDL; IMDS; Intermedin

ADM2 belongs to a family of calcitonin related peptide hormones important for regulating diverse physiologic functions and the chemical composition of fluids and tissues. ADM2 contains a dibasic cleavage site, followed by a 47-amino acid mature peptide hormone sequence and an alpha-amidation donor glycine at the C terminus.
Immunohistochemical analysis of several mouse tissues detected Adm2 in pituitary and stomach. PCR analysis of a human gastrointestinal panel detected ADM2 in almost all regions examined. Immunohistochemical staining showed ADM2 in the muscularis mucosae layer of stomach. Western blot analysis of transfected embryonic kidney cells found mature ADM2 secreted into the culture medium; the apparent molecular mass was about 5.0 kD.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Hu01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Hu01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Hu01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Hu01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Hu01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Mu01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Mu01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Mu01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Mu01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Mu01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Ra01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Ra01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Ra01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Ra01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Ra01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Ca01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Ca01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Ca01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Ca01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Ca01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Po01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Po01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Po01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Po01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Po01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Bo01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Bo01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Bo01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Bo01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Bo01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Rb01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Rb01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Rb01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Rb01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Rb01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO089Mo01 Recombinant Adrenomedullin 2 (ADM2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO089Mo01 Monoclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IP.
PAO089Mo01 Polyclonal Antibody to Adrenomedullin 2 (ADM2) WB; IHC; ICC; IF.
Assay Kits CLO089Mo01 CLIA Kit for Adrenomedullin 2 (ADM2) CLIA assay for Antigen Detection
ELO089Mo01 ELISA Kit for Adrenomedullin 2 (ADM2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes."
J. Biol. Chem. 279:7264-7274(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator."
FEBS Lett. 556:53-58(2004) [PubMed] [Europe PMC] [Abstract]

"Immunocytochemical localization of adrenomedullin 2/intermedin-like immunoreactivity in human hypothalamus, heart and kidney."
Peptides 27:1383-1389(2006) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 22."
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]