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Acetylcholinesterase Associated Protein (ACHAP)

CUTA; C6orf82; CutA Divalent Cation Tolerance Homolog; Brain acetylcholinesterase putative membrane anchor

CutA is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs.CutA may play a role in anchoring acetylcholinesterase in neuronal cell membranes and may be involved in signal transduction.
CutA is a ubiquitous trimeric protein, homologous to the bacterial CutA1 protein that belongs to an operon involved in resistance to divalent ions ("copper tolerance A"). The function of this protein in plants and animals is unknown, and several hypotheses concerning its subcellular localization have been proposed.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Hu01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Hu01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Hu01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Hu01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Hu01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Mu01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Mu01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Mu01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Mu01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Mu01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Ra01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Ra01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Ra01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Ra01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Ra01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Ca01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Ca01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Ca01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Ca01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Ca01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Po01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Po01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Po01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Po01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Po01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Bo01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Bo01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Bo01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Bo01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Bo01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Rb01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Rb01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Rb01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Rb01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Rb01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO080Mo01 Recombinant Acetylcholinesterase Associated Protein (ACHAP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO080Mo01 Monoclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IP.
PAO080Mo01 Polyclonal Antibody to Acetylcholinesterase Associated Protein (ACHAP) WB; IHC; ICC; IF.
Assay Kits CLO080Mo01 CLIA Kit for Acetylcholinesterase Associated Protein (ACHAP) CLIA assay for Antigen Detection
ELO080Mo01 ELISA Kit for Acetylcholinesterase Associated Protein (ACHAP) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization."
J. Neurochem. 74:2146-2153(2000) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Two distinct proteins are associated with tetrameric acetylcholinesterase on the cell surface."
J. Biol. Chem. 275:34260-34265(2000) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."
J. Proteome Res. 12:573-584(2013) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Divalent cation tolerant protein CUTA from Homo sapiens O60888."
Submitted (SEP-2004) to the PDB data bank