Call Now

Engrailed Homeobox Protein 2 (EN2)

AUTS1

Prostate cancer (PC) is the second most common cause of cancer related death in men. A number of key limitations with prostate specific antigen (PSA), currently the standard detection test, has justified evaluation of new biomarkers.Engrailed-2 (EN2) protein, a homeodomain-containing transcription factor expressed in PC cell lines and secreted into the urine by PC in men. EN2 was expressed and secreted by PC cell lines and PC tissue but not by normal prostate tissue or stroma. The presence of EN2 in urine was highly predictive of PC, with a sensitivity of 66% and a specificity of 88.2%, without requirement for DRE. There was no correlation with PSA levels.Urinary EN2 is a highly specific and sensitive candidate biomarker of prostate cancer.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins N777Hu01 Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies MN777Hu21 Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
PN777Hu01 Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits KEN777Hu ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engrailed Homeobox Protein 2 (EN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engrailed Homeobox Protein 2 (EN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engrailed Homeobox Protein 2 (EN2) CLIA assay for Antigen Detection

Reference

"Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions."
Dev. Genet. 13:345-358(1992) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 7: DNA sequence and biology."
Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Isolation and chromosomal localization of the human En-2 gene."
Genomics 4:225-231(1989) [PubMed] [Europe PMC] [Abstract]

"Identification of homeobox genes expressed in human haemopoietic progenitor cells."
Gene 144:213-219(1994) [PubMed] [Europe PMC] [Abstract]

"Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus."
Am. J. Hum. Genet. 77:851-868(2005) [PubMed] [Europe PMC] [Abstract]