Slingshot Homolog 3 (SSH3)

SSH3L; SSH-like protein 3; Protein phosphatase Slingshot homolog 3

SPN	N577
HGNC	30581
MGI	2683546
PubMed	21868701
RGD	1308679
UniProt	Q8TE77
Wiki	SSH3

The ADF (actin-depolymerizing factor)/cofilin family is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo.

Transcript analysis suggested that at least 6 polypeptides would be produced from these genes. SSH1 encodes 3 isoforms, SSH1L, SSH1S, and SSH1B, and SSH2 encodes 2 isoforms, SSH2 and SSH2B. The SSH3 protein has 471 amino acids. Besides the catalytic domain, 2 other domains are conserved between Drosophila ssh and the human SSHs (domains A and B) and are unique to the SSH family.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	N577Hu01	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	MN577Hu21	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	PN577Hu01	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	KEN577Hu	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Slingshot Homolog 3 (SSH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Slingshot Homolog 3 (SSH3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Slingshot Homolog 3 (SSH3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Slingshot Homolog 3 (SSH3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Slingshot Homolog 3 (SSH3)	CLIA assay for Antigen Detection

Reference

"Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin."
Cell 108:233-246(2002) [PubMed] [Europe PMC] [Abstract]

"Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin."
Genes Cells 8:811-824(2003) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]