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Brother Of CDO Homolog (BOC)
Brother Of CDO Homolog (BOC)
The 1,113-amino acid BOC protein contains 4 Ig repeats, followed by 3 FNIII repeats, a single-pass transmembrane domain, and a 238-residue intracellular region. The domain structure of BOC is similar to that of CDON, and the 2 proteins share 38 to 80% amino acid identity in the individual extracellular domains. The intracellular region of BOC, however, is unrelated to that of CDON. In situ hybridization analysis revealed that, like Cdon, Boc was strongly expressed in dorsal neural tube, somites, and dermomyotomes during murine embryonic development. Northern blot analysis detected a 5-kb transcript in myoblasts in the absence of Ras (190020) transformation. BOC was expressed in most adult human tissues tested, with highest levels in skeletal muscle and small intestine.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
N128Mu01
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
PN128Mu01
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Brother Of CDO Homolog (BOC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Brother Of CDO Homolog (BOC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Brother Of CDO Homolog (BOC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Brother Of CDO Homolog (BOC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Brother Of CDO Homolog (BOC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Brother Of CDO Homolog (BOC) CLIA assay for Antigen Detection
Reference
"BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation." EMBO J. 21:114-124(2002) [PubMed ] [Europe PMC ] [Abstract ]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites." Protein Sci. 13:2819-2824(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation." Proc. Natl. Acad. Sci. U.S.A. 100:3989-3994(2003) [PubMed ] [Europe PMC ] [Abstract ]
"All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner." J. Biol. Chem. 285:24584-24590(2010) [PubMed ] [Europe PMC ] [Abstract ]
"The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed ] [Europe PMC ] [Abstract ]
