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Dishevelled, Dsh Homolog 3 (DVL3)

Segment polarity protein dishevelled homolog DVL-3

DVL3is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.DVL3 encodes a predicted 716-amino acid polypeptide that shows 74% nucleotide homology with human DVL1 and 71% homology with the mouse Dvl1 gene. DVL1 and DVL3 share 64% amino acid identity. PCR carried out using DNA from rodent human somatic cell hybrids and DVL3 specific primers led to the assignment of DVL3 to human chromosome 3. Hybridization of poly(A) mRNA with the DVL3 cDNA revealed a 2.9-kb transcript with abundant expression in skeletal muscle, pancreas and heart.The 5.9-kb form was abundant in fetal tissues but the 5.0-kb form was absent from these tissues.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Hu01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Hu01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Hu01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Hu01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Hu01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Mu01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Mu01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Mu01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Mu01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Mu01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Ra01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Ra01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Ra01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Ra01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Ra01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Ca01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Ca01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Ca01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Ca01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Ca01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Po01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Po01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Po01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Po01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Po01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Bo01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Bo01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Bo01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Bo01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Bo01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Rb01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Rb01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Rb01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Rb01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Rb01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM933Mo01 Recombinant Dishevelled, Dsh Homolog 3 (DVL3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM933Mo01 Monoclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IP.
PAM933Mo01 Polyclonal Antibody to Dishevelled, Dsh Homolog 3 (DVL3) WB; IHC; ICC; IF.
Assay Kits CLM933Mo01 CLIA Kit for Dishevelled, Dsh Homolog 3 (DVL3) CLIA assay for Antigen Detection
ELM933Mo01 ELISA Kit for Dishevelled, Dsh Homolog 3 (DVL3) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene."
Hum. Mol. Genet. 5:953-958(1996) [PubMed] [Europe PMC] [Abstract]

"cDNA cloning of a human dishevelled DVL-3 gene, mapping to 3q27, and expression in human breast and colon carcinomas."
Biochem. Biophys. Res. Commun. 239:510-516(1997) [PubMed] [Europe PMC] [Abstract]

"Human dishevelled genes constitute a DHR-containing multigene family."
Genomics 42:302-310(1997) [PubMed] [Europe PMC] [Abstract]

"Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."
DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Regulation of the Wnt signaling pathway by disabled-2 (Dab2)."
EMBO J. 22:3084-3094(2003) [PubMed] [Europe PMC] [Abstract]

"Identification of the Wnt signaling activa