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V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1)

AMYB; A-myb; MYBA; Myb-related protein A

Nomura et al. (1988) isolated and characterized cDNA clones for 2 human MYB-related genes, and BMYB. Using probes in Southern blot analysis of rodent-human hybrid DNAs, Barletta et al. (1991) localized the MYBL1 locus to 8cen-q22 and refined the localization to 8q22-q23 by in situ hybridization. MYBL1 mRNA is expressed mainly in testis and peripheral blood leukocytes. AMYB could activate transcription from the promoter-containing MYB-binding sites in all cells examined. In addition to the 2 domains (a DNA-binding domain and a transcriptional activation domain), 2 negative regulatory domains were identified in the MYBL1 gene. These results indicated that the gene functions as a transcriptional activator and that the regulatory mechanism of gene activity is similar to that of the MYB gene.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Hu01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Hu01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Hu01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Hu01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Hu01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Mu01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Mu01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Mu01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Mu01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Mu01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Ra01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Ra01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Ra01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Ra01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Ra01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Ca01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Ca01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Ca01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Ca01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Ca01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Po01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Po01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Po01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Po01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Po01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Bo01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Bo01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Bo01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Bo01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Bo01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Rb01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Rb01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Rb01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Rb01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Rb01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM627Mo01 Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM627Mo01 Monoclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IP.
PAM627Mo01 Polyclonal Antibody to V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) WB; IHC; ICC; IF.
Assay Kits CLM627Mo01 CLIA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) CLIA assay for Antigen Detection
ELM627Mo01 ELISA Kit for V-Myb Myeloblastosis Viral Oncogene Homolog Like Protein 1 (MYBL1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Isolation of human cDNA clones of myb-related genes, A-myb and B-myb."
Nucleic Acids Res. 16:11075-11089(1988) [PubMed] [Europe PMC] [Abstract]

"The human A-myb protein is a strong activator of transcription."
Oncogene 9:2469-2479(1994) [PubMed] [Europe PMC] [Abstract]

"DNA binding and transactivation activity of A-myb, a C-myb-related gene."
Cancer Res. 54:6512-6516(1994) [PubMed] [Europe PMC] [Abstract]

"Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence."
Mol. Cell 26:539-551(2007) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]